PREPROCESSING

Comprehensive preprocessing techniques for Neuropixels neural recordings.

Skills
Scientific
3

What it does and how to use it

A skill that teaches Claude Code to do scientific tasks well. It is packaged knowledge the model uses whenever it is relevant.

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Install (Claude Code)

mkdir -p .claude/skills/preprocessing && curl -fsSL https://doutorai.pt/data/lib/skills__preprocessing.md -o .claude/skills/preprocessing/SKILL.md

Paste this command into the terminal, in your project folder, and the component installs automatically.

Content

# Neuropixels Preprocessing Reference

Comprehensive preprocessing techniques for Neuropixels neural recordings.

## Standard Preprocessing Pipeline

```python
import spikeinterface.full as si

# Load raw data
recording = si.read_spikeglx('/path/to/data', stream_id='imec0.ap')

# 1. Phase shift correction (for Neuropixels 1.0)
rec = si.phase_shift(recording)

# 2. Bandpass filter for spike detection
rec = si.bandpass_filter(rec, freq_min=300, freq_max=6000)

# 3. Common median reference (removes correlated noise)
rec = si.common_reference(rec, reference='global', operator='median')

# 4. Remov

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