basic_inference

If not provided, all genes are considered potential regulators.

Skills
Scientific
2

What it does and how to use it

A skill that teaches Claude Code to do scientific tasks well. It is packaged knowledge the model uses whenever it is relevant.

Install the skill (command above).
In Claude Code, describe what you need - the skill turns on by itself when the context fits.
No commands to memorize: you talk in plain language and the skill does the rest.

Install (Claude Code)

mkdir -p .claude/skills/basic-inference && curl -fsSL https://doutorai.pt/data/lib/skills__basic-inference.md -o .claude/skills/basic-inference/SKILL.md

Paste this command into the terminal, in your project folder, and the component installs automatically.

Content

# Basic GRN Inference with Arboreto

## Input Data Requirements

Arboreto requires gene expression data in one of two formats:

### Pandas DataFrame (Recommended)
- **Rows**: Observations (cells, samples, conditions)
- **Columns**: Genes (with gene names as column headers)
- **Format**: Numeric expression values

Example:
```python
import pandas as pd

# Load expression matrix with genes as columns
expression_matrix = pd.read_csv('expression_data.tsv', sep='\t')
# Columns: ['gene1', 'gene2', 'gene3', ...]
# Rows: observation data
```

### NumPy Array
- **Shape**: (observations, genes)
- **Requ

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