# models-multimodal

> This document covers models for joint analysis of multiple data modalities in scvi-tools.

- Source: https://doutorai.pt/en/components/skills__models-multimodal
- Type: Skills
- Category: Scientific
- Downloads: 0
- Site: Doutor AI (https://doutorai.pt/en) - AI tools for small businesses

An open-source community component, curated and adapted by Doutor AI.

## What it does and how to use it

A **skill** that teaches Claude Code to do scientific tasks well. It is packaged knowledge the model uses whenever it is relevant.

1. Install the skill (command above).
2. In Claude Code, describe what you need - the skill turns on by itself when the context fits.
3. No commands to memorize: you talk in plain language and the skill does the rest.

## Install (Claude Code)

```bash
mkdir -p .claude/skills/models-multimodal && curl -fsSL https://doutorai.pt/data/lib/skills__models-multimodal.md -o .claude/skills/models-multimodal/SKILL.md
```

Paste this command into the terminal, in your project folder, and the component installs automatically.

## Content

```
# Multimodal and Multi-omics Integration Models

This document covers models for joint analysis of multiple data modalities in scvi-tools.

## totalVI (Total Variational Inference)

**Purpose**: Joint analysis of CITE-seq data (simultaneous RNA and protein measurements from same cells).

**Key Features**:
- Jointly models gene expression and protein abundance
- Learns shared low-dimensional representations
- Enables protein imputation from RNA data
- Performs differential expression for both modalities
- Handles batch effects in both RNA and protein layers

**When to Use**:
- Analyzing CITE-se

- 🔒 Full content on the Pro plan (€7.99/month) -
```

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Content by Doutor AI (https://doutorai.pt/en). When quoting, please cite the source: https://doutorai.pt/en/components/skills__models-multimodal