# models-atac-seq

> This document covers models for analyzing single-cell ATAC-seq and chromatin accessibility data in scvi-tools.

- Source: https://doutorai.pt/en/components/skills__models-atac-seq
- Type: Skills
- Category: Scientific
- Downloads: 0
- Site: Doutor AI (https://doutorai.pt/en) - AI tools for small businesses

An open-source community component, curated and adapted by Doutor AI.

## What it does and how to use it

A **skill** that teaches Claude Code to do scientific tasks well. It is packaged knowledge the model uses whenever it is relevant.

1. Install the skill (command above).
2. In Claude Code, describe what you need - the skill turns on by itself when the context fits.
3. No commands to memorize: you talk in plain language and the skill does the rest.

## Install (Claude Code)

```bash
mkdir -p .claude/skills/models-atac-seq && curl -fsSL https://doutorai.pt/data/lib/skills__models-atac-seq.md -o .claude/skills/models-atac-seq/SKILL.md
```

Paste this command into the terminal, in your project folder, and the component installs automatically.

## Content

```
# ATAC-seq and Chromatin Accessibility Models

This document covers models for analyzing single-cell ATAC-seq and chromatin accessibility data in scvi-tools.

## PeakVI

**Purpose**: Analysis and integration of single-cell ATAC-seq data using peak counts.

**Key Features**:
- Variational autoencoder specifically designed for scATAC-seq peak data
- Learns low-dimensional representations of chromatin accessibility
- Performs batch correction across samples
- Enables differential accessibility testing
- Integrates multiple ATAC-seq datasets

**When to Use**:
- Analyzing scATAC-seq peak count matr

- 🔒 Full content on the Pro plan (€7.99/month) -
```

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Content by Doutor AI (https://doutorai.pt/en). When quoting, please cite the source: https://doutorai.pt/en/components/skills__models-atac-seq